APP Insight: Discussing Exercise as a Complement to IBS-C Treatment

July 2025

In this episode, Mary Clarke, a GI motility nurse practitioner based in San Diego, discusses the powerful role of complementary and alternative therapies—especially exercise—in managing Irritable Bowel Syndrome (IBS). With a focus on IBS-C (constipation-predominant IBS), Mary explains how regular physical activity can improve gastrointestinal motility, reduce abdominal pain and bloating, support emotional well-being by lowering stress levels, and positively influence the gut microbiome. She reviews different forms of aerobic and low-impact exercise, including walking, cycling, swimming, and yoga, and provides practical strategies for patients at all activity levels to build sustainable routines. Mary also highlights the physiological mechanisms behind exercise-induced gut improvement, including cytokine regulation, enhanced digestion, improved nutrient absorption, and reduced inflammation. This video offers actionable guidance for clinicians and patients looking to incorporate lifestyle interventions into IBS treatment plans. Learn more at the GHAPP website or by visiting the GHAPP ACE App.